SARMs 101

Everything you need to know about SARMs… from Global SEO on Vimeo.

Why should you use SARMs?

SARMs offer three main benefits: increased bone density, increased muscle mass and decreased body fat. Although it may seem from these three benefits that SARMs are only useful for athletes and bodybuilders, this isn’t exactly true, and there are millions of people across the globe that could benefit from SARM usage. Those with muscle wasting diseases, sports induced injuries, burns victims, weakness, body wasting due to diseases like HIV or cancer and even the elderly (due to their continued loss of body and muscle mass). Despite the fact that there are a plethora of drugs that are available for all of the previously mentioned conditions, SARMs have several advantages over many of these in that they are non-methylated nor do they interact with the aromatase or 5-alpha reductase enzymes, meaning they are non-liver toxic, will not cause estrogen related side effects nor convert into more potent androgens (and therefore will not exert any androgenic related side effects). These negative effects are very common when taking anabolic steroids (and some pro hormones), therefore SARM usage can reduce or even completely eliminate these from occurring. This is the main reason why anabolic steroid treatment was halted for many of the aforementioned conditions – there were simply too many side effects. SARMs on the other hand would help to maximise healthy and vitality without these side effects.


If we compare two clinical trials – one on SARMs and one on testosterone (at supra-physiological levels) – we can see the difference between the two, both in terms of positive and negative effects. SARMs typically increase fat-free mass by 1-2kg over the course of 6 weeks, whereas 300-600mg of testosterone for the same period will result in double that. This isn’t surprising due to the fact that 300-600mg of testosterone will put a man’s testosterone levels several times the upper natural limit. In addition, SARM trials have been carried out on those that are not weight training nor eating high amounts of protein, whereas the aforementioned trial conducted on testosterone was carried out on men who trained. In addition, testosterone usage will often lead to a decrease in HDL and an increase in LDL.

Like testosterone, some SARMs may also switch on AMPK, which will result in fat loss (through lipolysis and fat oxidation). While testosterone (and other androgens) typically do this at a greater rate, they also come with the side effects of reducing both LH and FSH, which SARMs do not do unless used at extremely high doses (doses that very few would use and certainly not within the medical field).

Another positive impact that SARMs appear to induce are related to bone, both in terms of increase bone formation and decreasing bone turnover, which suggests that SARMs may have a place in the treatment of osteoporosis. Those that are at the biggest risk from osteoporosis are post-menopausal women, and as androgens can not be used to treat such ailments in females it becomes apparent that SARMs may have a place.

As you can see, SARMs have numerous positive effects without many of the negative effects associated with anabolic steroid usage, and can be used both medically and for physique and body enhancement. If you’re seeking an alternative to anabolic steroids or a steroid user that wants to avoid many of the native side effects of steroids then SARMs should seriously be considered. This article isn’t exhaustive by any means, so if you’re seeking more detailed information on SARMs then we suggest visiting the following website:

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